Venture Business
ISO 9001:2015
NCLBIO Co., Ltd.
20, Hoseo-ro 79beon-gil,
Baebang-eup, Asan-si,
Chungcheongnam-do,
Republic of Korea

TEL : +82-41-534-5600
E-mail : nclbio@nclbio.com

Copyright 2017 NCLBIO.
All Rights Reserved.

TECHNOLOGY

Utilizing our cutting-edge of biotechnology and protein engineering technology,
we research and develop innovative active ingredient to
apply for cosmetic and pharmaceutical.

Peptide

NCLBIO develops and produces the following peptides utilizing biotechnology / molecular biology / chemistry / protein engineering technology.

이미지

NCL EGF(Epidermal Growth Factor)

  • INCI Namesh-Oligopeptide-1

    function- Skin improvement and anti-aging
    - Excellence efficacy in anti-aging and skin wrinkle improvement by skin cell reservation and collagen synthesis
    - In short time, excellence efficacy in skin tone improvement and
    skin smoothness.

  • Trade Name NCL-EGF(Epidermal Growth Factor)
    Source Recombinant protein produced by E. Coli
    Appearance Clear solution
    Purity >98% by SDS-PAGE
    Amino Acid 53 a.a
    MW 6.2 kDa
    pH 5.8±0.5
    Preservative Hexanediol 2%
  • Relative HDF Proliferation(A490)

    NCL EGF이미지
  • NCL EGF이미지
  • Photo before and after use

    NCL EGF이미지
  • NCL EGF이미지

NCL bFGF(Fibroblast Growth Factor)

  • INCI Namesh-Polypeptid-1

    Function- Regeneration of skin cell and stimulate gene expression related in skin recovery
    - Excellence efficacy in skin wrinkle improvement by
    dermal cell regeneration and collagen synthesis.
    - By stimulation of Hyaluronic acid and Elastin synthesis,
    excellence efficacy in skin moisturizing and skin elasticity recovery

  • Trade Name NCL-bFGF(Fibroblast Growth Factor)
    Source Recombinant protein produced by E. Coli
    Appearance Clear solution
    Purity >98% by SDS-PAGE
    Amino Acid 155 a.a
    MW 17.3 kDa
    pH 7.2±0.5
    Preservative Hexanediol 2%

bFGF

Fibroblast Growth Factor

  • Stimulate collagen synthesis
    (Wrinkle improvement)

  • Stimulate elastin synthesis
    (Enhance skin elasticity)

  • Activate skin cell activity

  • Hydrophilic strengthening
    (Moisturizing effect)

  • Wound healing

  • Skin regeneration after peeling

NCL AHP-8

  • INCI NameAcetyl Hexapeptide-8

    Function-Referred to as a 'Botox peptide'
    -Anti-wrinkle and anti-aging
    -Enhancing moisture and elasticity in skin by stimulating collagen synthesis.

  • Trade Name NCL AHP-8
    Purity ≥ 98%
    Chemical formula C34H60N14O12S
    MW 889.00
    CAS Number 616204-22-9
  • After using Acetyl Hexapeptide-8, winkle depth is reduced

    NCL EGF이미지
  • NCL AHP-8 structural formula

    NCL EGF이미지

NCL CTP-1

  • INCI NameCopper Tripeptide-1

    Function-Regulating gene expression of skin cell
    -Anti-wrinkle by collagen synthesis
    -Anti-oxidation, anti-inflammatory and anti-aging by regulating gene expression of skin cell

  • Trade Name NCL CTP-1
    Purity ≥ 98%
    Chemical formula C14H24N6O4Cu
    MW 403.92
  • Fibroblast proliferation activity by GHK-Cu treatment

    NCL EGF이미지
  • Collagen gene expression level by GHK-Cu treatment

    NCL EGF이미지
  • NCL CTP-1 structural formula

    NCL EGF이미지

NCL TP-21

  • INCI NameTetrapeptide-21

    Function-Excellence efficacy for wrinkle improvement
    -Stimulate collagen synthesis related in skin wrinkle improvement.
    -Stimulate gene expression of Hyaluronic acid related in skim moisturizing and improvement.

  • Trade Name NCL TP-21
    Purity ≥ 98%
    Chemical formula C15H27N5O7
    MW 389.40
    CAS Number 960608-17-7
  • Improvement of skin elasticity after 8 weeks

    NCL EGF이미지
  • Skin volume after 8weeks of application compared to start value

    NCL EGF이미지
  • NCL TP-21 structural formula

    NCL EGF이미지

NCL PPP-4

  • INCI NamePalmitoyl Pentapeptide-4

    Function-Derived from natural compound Matrikine and commercialized as MATRIXYL peptide
    -Stimulate collagen synthesis in skin cell.
    -Improvement of skin wrinkle and increase moisture content in skin.

  • Trade Name NCL PPP-4
    Purity ≥ 98%
    Chemical formula C39H75N7O10
    MW 802.07
    CAS Number 214047-00-4
  • Collagen synthesis rate

    NCL EGF이미지
  • Collagen synthesis rate

    NCL EGF이미지

Extra peptide

  • INCI NamePalmitoyl Tripeptide-1

    Function-Protect skin from skin dryness and external irritation
    -Protect skin from external irritation
    -Improve skin texture by stimulation of collagen synthesis
    -Stimulate skin tissue and reduce wrinkles because it is analogous to collagen structure

  • INCI NamePalmitoyl Tetrapeptide-7

    Function-Protect skin from skin dryness and external irritation
    -Reduce production of interleukin-6 (IL-6) in skin cell, keratinocyte and fibroblast
    -Reduce agents that cause skin aging and saggy skin
    -Stimulate skin rejuvenation

  • INCI NameNonapeptide-1

    Function-Protect skin from skin dryness and external irritation
    -Suppress melanin synthesis
    -Suppress skin pigmentation

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